The David and Lucile Packard Foundation gave a $100 million grant last week to start a five-year fund-raising campaign to benefit the Lucile Packard Children’s Hospital and the pediatric research and training programs of the Stanford University School of Medicine.

The gift is believed to be the largest ever to a U.S. children’s hospital and is in conjunction with the Lucile Packard Foundation’s $500 million fund-raising campaign announced immediately before Stanford recessed for Thanksgiving.

The donation was Stanford’s second significant gift from a foundation this year. On May 2 the Hewlett Foundation gave the school $400 million, a gift that was the largest donation to an American university until Intel founder Gordon Moore gave $600 million to the California Institute of Technology.

Yale President Richard Levin, a Hewlett Foundation board member, said the gifts are off the chart for foundation gifts.

“Those are very big gifts,” Levin said. “I am hard pressed to think of foundation gifts larger than $10 million [at Yale].”

–Elise Jordan