The disappearance of Annie Le GRD ’13 remains “the most perplexing mystery,” University Vice President and Secretary Linda Lorimer wrote in a campuswide e-mail message Saturday night.

Lorimer reiterated many of the same themes she touched on in her earlier comments at a press conference this afternoon with representatives from the Federal Bureau of Investigation, the Yale Police Department, the New Haven Police Department and the Connecticut State Police.

As at the press conference, she noted that items found at 10 Amistad St., where Le was last seen Tuesday morning, are being analyzed but that a connection to Le has not been established.

“As I am sure you understand, at this delicate time it is particularly unhelpful to begin speculating or jumping to conclusions,” Lorimer wrote in her message to the community. “If it does develop that a crime occurred, we want to do everything to ensure that the investigation proceeds as swiftly and completely as possible.”

Lorimer also said she has been in touch with Le’s parents and her fiance, Columbia University graduate student Jonathan Widawsky, who are all cooperating with the investigation.

Informational sessions about Le’s investigation with University Deputy Secretary Martha Highsmith, who oversees campus security, have already been held at 10 Amistad St. and elsewhere at the School of Medicine, and more will take place “when the deans think they can be useful,” Lorimer wrote.